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Exomide Exosomes For Hair Growth

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Represent a revolutionary advancement in the field of regenerative medicine, offering a promising solution to hair loss and promoting hair regrowth.

A revolutionary advancement in the field of Regenerative Medicine

​Hair Growth Exosomes that are delivered into the scalp by Exomides

Represent a revolutionary advancement in the field of regenerative medicine, offering a promising solution to hair loss and promoting hair regrowth. Exosomes are extracellular vesicles secreted by cells that contain a potent cargo of growth factors, proteins, and nucleic acids. When applied to the scalp, hair growth exosomes stimulate the proliferation of hair follicle cells, enhance tissue regeneration, and promote a healthier scalp environment conducive to robust hair growth.

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Here’s why Hair Growth Exosomes are gaining traction in the market

​Hair growth exosomes contain growth factors such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and fibroblast growth factor (FGF), which play key roles in stimulating hair follicle growth and angiogenesis. By delivering these bioactive molecules directly to the scalp, exosomes promote the proliferation of hair follicle cells, prolong the anagen (growth) phase of the hair cycle, and induce the formation of new blood vessels to support hair growth.

​Unlike traditional hair restoration procedures such as hair transplantation or laser therapy, hair growth exosomes offer a non-invasive and pain-free solution to hair loss. Topical application or injection of exosome-rich solutions bypasses the need for surgical intervention, making it an attractive option for individuals seeking minimally invasive treatments for hair regrowth.

​Hair growth exosomes can be tailored to meet the specific needs of individual patients. Clinicians can customize exosome formulations by adjusting the concentration of growth factors and other bioactive components to optimize efficacy and address unique hair loss concerns, such as male pattern baldness, alopecia areata, or thinning hair.

Exosomes are derived from mesenchymal stem cells or other cell types cultured in laboratory settings. As a natural component of cellular communication, exosomes exhibit low immunogenicity and are well-tolerated by the body. This makes them a safe and biocompatible option for hair restoration treatments, with minimal risk of adverse reactions or side effects.

Hair growth exosomes can complement existing hair loss treatments, such as topical minoxidil or oral finasteride. When used in combination with other modalities, exosome therapy may enhance the efficacy of hair regrowth treatments and improve overall outcomes for patients with varying degrees of hair loss.

​Before and After Treatment Exomide Scalp

Contents – Exosome 10 Billion

  • 17 type of Amino acid: lysine, phenylalanine, valine, leucine, isoleucine, threonine, methionine, histidine, arginine, glycine, serine, proline, tyrosine, cysteine, alanine, aspartic acid, glutamic acid
  • 6 type of peptide: palmitoyl pentapeptide-4, palmitoyl tripeptide-1, hexapeptide-9, acetyl hexapeptide-8, tripeptide-1, copper tripeptide-1
  • Pine needle, cypress leaf, arborvitae leaf, and ginkgo leaf extracts
  • Ecklonia Cava Extract
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References

  1. Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., … & Corteling, R. L. (2018). Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of extracellular vesicles, 7(1), 1535750.
  2. Yáñez-Mó, M., Siljander, P. R., Andreu, Z., Zavec, A. B., Borràs, F. E., Buzas, E. I., … & De Wever, O. (2015). Biological properties of extracellular vesicles and their physiological functions. Journal of extracellular vesicles, 4(1), 27066.
  3. Colombo, M., Raposo, G., & Théry, C. (2014). Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annual review of cell and developmental biology, 30, 255-289.
  4. Mathieu, M., Martin-Jaular, L., Lavieu, G., & Théry, C. (2019). Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication. Nature cell biology, 21(1), 9-17.
  5. Kalluri, R., & LeBleu, V. S. (2020). The biology, function, and biomedical applications of exosomes. Science, 367(6478), eaau6977.
  6. van Niel, G., D’Angelo, G., & Raposo, G. (2018). Shedding light on the cell biology of extracellular vesicles. Nature Reviews Molecular Cell Biology, 19(4), 213-228.
  7. Lötvall, J., Hill, A. F., Hochberg, F., Buzás, E. I., Di Vizio, D., Gardiner, C., … & Kurochkin, I. V. (2014). Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. Journal of extracellular vesicles, 3(1), 26913.
  8. Kowal, J., Tkach, M., & Théry, C. (2014). Biogenesis and secretion of exosomes. Current opinion in cell biology, 29, 116-125.
  9. Tkach, M., & Théry, C. (2016). Communication by extracellular vesicles: where we are and where we need to go. Cell, 164(6), 1226-1232.
  10. Zhang, H., Freitas, D., Kim, H. S., Fabijanic, K., Li, Z., Chen, H., … & Lyden, D. (2018). Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation. Nature cell biology, 20(3), 332-343.
  11. Willms, E., Johansson, H. J., Mäger, I., Lee, Y., Blomberg, K. E., Sadik, M., … & Gho, Y. S. (2016). Cells release subpopulations of exosomes with distinct molecular and biological properties. Scientific reports, 6(1), 1-12.
  12. Properzi, F., Logozzi, M., Fais, S., & Exosomics, S. (2013). Exosomes: the future of biomarkers in medicine. Biomarkers in medicine, 7(5), 769-778.
  13. Zhang, H., Lyden, D., & Asymmetric, F. F. F. F. (2016). Decoding extracellular vesicle biology through proteomic and lipidomic analysis. Nature Reviews Nephrology, 13(5), 1-21.
  14. Lener, T., Gimona, M., Aigner, L., Börger, V., Buzas, E., Camussi, G., … & Giebel, B. (2015). Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper. Journal of extracellular vesicles, 4(1), 30087.
  15. Mateescu, B., Kowal, E. J., van Balkom, B. W., Bartel, S., Bhattacharyya, S. N., Buzás, E. I., … & Gardiner, C. (2017). Obstacles and opportunities in the functional analysis of extracellular vesicle RNA—an ISEV position paper. Journal of extracellular vesicles, 6(1), 1286095.

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